The cost of isopropyl myristate depends upon the length of hair involved and the amount of solution used. Minimal packaging drum swallowing large amounts may be harmful. Hallstar ipmnf is a multifunctional emollient, solvent, spreading agent, penetrant synthetically produced ester of vegetal myristic acid and petrochemical isopropyl alcohol that conforms to the requirements of the national formulary monograph for isopropyl myristate. Using a homogeneous reaction phase, nonspecific lipase derived from candida antartica, marketed as novozym 435, was determined to be most suitable for the enzymatic synthesis of isopropyl myristate. Isopropyl myristate is perfectly safe as a cosmetic ingredient and there are no issues with it as far as end users are concerned. Proprietary ingredients indicated as hazardous have been assessed under standards for workplace safety. Other local effects have included nasal and lung irritation during inhalation of aerosols in monkeys and rats, acne development after application to rabbit skin, and increased permeability of human.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrat. Viscous products, such as creams and ointments, can be difficult to filter and are normally diluted in a sterile solvent, such as isopropyl myristate ipm. Product and company identification product name citron extra product code 4391 recommended use personal care chemical nature mixture information on manufacturer emergency telephone number chemsearch div. Isopropyl myristate, with the chemical formula ch 3 ch 2 12 cooch ch 3 2, is an ester of myristic acid, an essential fatty acid derived from palm kernel oil and isopropyl alcohol. Isopropyl myristate msds isopropyl myristate silver fern chemical. Methyl tetradecanoate, myristic acid methyl ester cas number 124107. This is a valuable attribute, as isopropyl myristate can help other skin healing chemicals to penetrate more deeply. It is important that you familiarize yourself with this chemical and take. Other local effects have included nasal and lung irritation during inhalation of aerosols in monkeys and rats, acne development after. Isopropyl myristate ipm is the ester of isopropyl alcohol and myristic acid. Isomyst, stepan d50, bisomel, ipm, tegester, crodamol i.
Used as an emollient in creams and lotions, isopropyl myristate ensures deep, quick penetration. Sds of isopropyl myristate, safety data sheets, cas 110270. Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in. Ipm 100, ipmex, ipmr, ipm, isopropyl tetradecanoate, myristic acid isopropyl ester cas number 110270. Isopropyl myristate, with the chemical formula ch 3 ch 2 12 cooch ch 3 2 4, is an ester of myristic acid, an essential fatty acid derived from palm kernel oil and isopropyl alcohol. This work was carried out to optimize the esterification process, between myristic acid and isopropanol, used for the production of isopropyl myristate in a reaction integrated distillation column. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. It is widely used as a nontoxic alternative for the control of head lice, as an emollient, and a lubricant. Hazards identification classification of the substance or mixture ghs classification. Green synthesis of isopropyl myristate in novel single. Green synthesis of isopropyl myristate in novel single phase. Amended safety assessment of alkyl esters as used in.
Refer to section 8 of msds for personal protection details. Isopropyl myristate is the ester of isopropyl alcohol and myristic acid. Comments off on toxicity profile for isopropyl myristate 2005 isopropyl myristate ipm has produced slight irritation of human skin, mild irritation of the rabbit eye and moderate irritation of rabbit skin. Isopropyl myristate name isopropyl myristate product identification naturalidentical flavouring substance chemical name isopropyl tetradecanoate chemical formulae c17h34o2 cas number 110270 fema number 3556 einecs number 2037514 physicochemical properties aspect colourless liquid organoleptic description characteristic. Isopropyl myristate finds many applications in food, cosmetic and pharmaceutical industries as an emollient, thickening agent, or lubricant. Isopropyl myristate is a light, colorless, oily liquid. Citron extra supercedes date 07282010 issuing date 02014 1. Isopropyl myristate, the ester of myristic acid and isopropyl alcohol, is also used in topical medications. Enzymatic synthesis of isopropyl myristate using immobilized lipase from bacillus cereus mtcc 8372. The substance identity section is calculated from substance identification information from all echa databases. Isopropyl myristate is being studied as a skin enhancer. Chemical product and company identification product name. This cosmetic ingredient produced minimal to mild skin irritation, minimal eye irritation in.
Isopropyl myristate 225 version 2 revision date 07112008 print date 07112008 page 4 8 requirements for storage areas and containers. It isipropyl the ester of isopropyl alcohol and myristic acid, both naturally occurring fatty acids. These products will have been purified before being used in the cosmetics to remove any residual isopropyl alcohol. These data suggest that biodegradation may be an important environmental fate process src. Find out more about isopropyl myristate, all the commercially available products, formulation examples and other related technical info. Isopropyl myristate production process optimization using response surface methodology and matlab article pdf available january 20 with 1,297 reads how we measure reads. Isopropyl myristate ipm has produced slight irritation of human skin, mild irritation of the rabbit eye and moderate irritation of rabbit skin.
Isopropyl lanolate 63393931 2641191 not listed not listed lanolin 8006540 2323486 not listed not listed isopropyl myristate 110270 2037514 not listed not listed carnauba wax 8015869 2323994 not listed not listed methylparaben 99763 2027857 not listed not listed propylparaben 943 2023077 not listed not listed. Import data and price of isopropyl myristate under hs code. Isopropyl myristate revision date 24jan2018 component casno weight % isopropyl myristate 110270 95 4. Steritest ez system sterility testing of products to be diluted in isopropyl myristate filtration is the pharmacopoeia method of choice for sterility testing. Steritest ez system sterility testing of products to be. Isopropyl myristate in mumbai, maharashtra get latest price. Enzymatic synthesis of isopropyl myristate using immobilized lipase from bacillus cereus mtcc 8372 article pdf available in acta microbiologica et immunologica hungarica 553. Isopropyl myristatecyclomethicone d5, is a topical formulation containing 5050 ww isopropyl myristatedecamethylcyclopentasiloxane. Thanks to its low viscosity and density, it has a high spreadability.
Isopropyl myristate in mumbai, maharashtra get latest. Composed of of isopropyl alcohol a propane derivative and myristic acid a naturallyoccurring fatty acid, isopropyl myristate is a popular cosmetic and pharmaceutical ingredient. Sigmaaldrich offers a number of isopropyl myristate products. Isopropyl myristate safety data sheet according to federal register vol. Material safety data sheet section 1 isopropyl myristate 1 chemical product and company identification msds name. It is generally safe, although some people with skin conditions may wish to avoid products containing. The frequency and concentration of use data are provided in. Safety data sheet northwest missouri state university. Isopropyl myristate msds material safety data sheet isopropyl myristate 1. Patient information sheet isopropyl myristate i003 your patch testing results indicate that you have a contact allergy to isopropyl myristate. It has been attacked by scaremongers either from ignorance or more likely from a cynical desire to sell inferior products at high prices.
Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in the closed bottle test 4. Ester of isopropyl alcohol and myristic acid vegetablederived. Identification of the substancemixture and of the companyundertaking. Apr 19, 2017 isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Ipm is used to dissolve lanolin and other oils, and is commonly used as a degreasant or softener in sunscreens, face creams and lipsticks. Keep containers tightly closed in a dry, cool and wellventilated place. Committee to evaluate drugs ced isopropyl myristate. Find patient medical information for isopropyl myristate bulk on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
It is manufactured through the condensation of isopropyl alcohol and mystic acid. Isopropyl myristate is found in several everyday beauty products and is generally considered safe for consumer use. Can a product be alcohol free while containing isopropyl. Isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. View detailed import data, price, monthly trends, major importing countries, major ports of isopropyl myristate under hs code 2915.
Despite its popularity with manufacturers, some side effects have been reported. Tetradecanoic acid, 1methylethyl ester chemical formula. Details of the supplier of the safety data sheet 2. Pdf isopropyl myristate production process optimization. Low viscosity fluid nongreasy emollient, tolerates wide ph range, compatible with most surfactants. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Sample recipe for isopropyl myristate making cosmetics. Firstaid measures general advice if symptoms persist, call a physician. Additionally, it can be used in bath oils, massage oils and perfumes. In cosmetics and personal care products, isopropyl myristate functions as a binder, and skinconditioning agent a emollient. It works great to easily, and painlessly, remove latex and silicone prosthetics. Final report on the safety assessment of myristyl myristate and isopropyl myristate acute oral and dermal toxicity tests indicated that myristyl myristate is nontoxic to rats.
Isopropyl myristate 110270 2037514 not listed not listed peg40 stearate 9004993 not listed not listed not listed water, purified 7732185 2317912 not listed not listed additional information. Cool containers with flooding quantities of water until well after fire is out. Long chain fatty acid esters, structurally similar to isopropyl myristate, were rapidly degraded by mixed sewage sludge1,2,3. Jun 08, 2011 isopropyl myristate is perfectly safe as a cosmetic ingredient and there are no issues with it as far as end users are concerned. Overall, the committee noted that isopropyl myristate is safer. Again, this is a lot and will probably last you a long time if youre using it the way i am. Any website that suggests this material is harmful should be ignored.
Amended safety assessment of alkyl esters as used in cosmetics. Isopropyl myristate and palmitate are esters formed from isopropyl alcohol and myristic and palmitic acids. Isopropyl myristate tetradecanoic acid, 1 methylethyl. Isopropyl myristate is a synthetic oil widely used in the cos. Final report on the safety assessment of myristyl myristate. It is also used as a pesticide against head lice which works. Its also perfect as a perfume diluent in place of other oils or alcohol. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired. Hence it finds broad application in topically applied cosmetic and pharmaceutical liquid, cream, lotion, powder and spray products. Sds safety data sheet isopropyl alcohol, 99% azer scientific inc 701 hemlock road morgantown pa 19543 610. If the labelling does not mention isopropyl alcohol as a component then it will not be present.
Isopropyl myristate can be used to dilute aroma chemicals. Isopropyl myristate liquid 125ml emollient, thickening agent, lubricant or moisturiser in beauty products allnatural ester used to empart a dry yet moisturising feel to skin creams recommendations. We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Containers which are opened must be carefully resealed and kept upright to prevent leakage. The frequency and concentration of use data are provided in table 8. Used as an emollient and lubricant in preshaves, aftershaves, shampoos, bath oils. Pdf enzymatic synthesis of isopropyl myristate using. Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in the closed bottle test4. Safety data sheet isopropyl myristate date prepared. Effectiveness of isopropyl myristatecyclomethicone d5. Lastly, isopropyl myristate is also believed to have strong skin penetrating properties. Isopropyl myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products.
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